最新心血管疾病预防PPT课件.ppt
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1、心血管疾病预防心血管疾病预防Cardiovascular Deaths by Region in 1990:Global Burdon of Disease Study,1990PredictedDue to CHDDue to StrokeIncrease by 2002No.(x 106)(%)(%)(%)Established market economies3.2532515Former socialist economies2.1503126India2.35220111China2.6305077Other Asia and Islands1.33429106Sub-Saharan
2、 Africa0.82647114Latin America and Caribbean0.84432120Middle Eastern Crescent1.34716129Cardiovascular Deaths,1990Non Cigarette SmokersNon Cigarette SmokersAll Cigarette SmokersAll Cigarette Smokers10 010 0797911411464641221224444135135AnginaAnginaPectorisPectorisMyocardialMyocardialInfarctionInfarct
3、ionSuddenSuddenDeathDeathOBS.OBS.EXP.EXP.Summary of NCEP ATP III*Guidelines LDL-C Goals*National Cholesterol Education Program Adult Treatment Panel III.Therapeutic lifestyle changes include:(1)dietary changes:reduced intake of saturated fats and cholesterol and enhanced LDL lowering with plant stan
4、ols/sterols and increased soluble fiber;(2)weight reduction;and(3)increased physical activity.Coronary heart disease.CHD risk equivalents comprise:diabetes,multiple risk factors that confer a 10-year risk for CHD 20%,and other clinical forms of atherosclerotic disease(peripheral arterial disease,abd
5、ominal aortic aneurysm,and symptomatic carotid artery disease).Major risk factors(exclusive of LDL-C)that modify LDL-C goals include cigarette smoking,hypertension(BP 140/90 mmHg or on antihypertensive medication),low HDL cholesterol(40 mg/dL),family history of premature CHD(CHD in male first-degree
6、 relative 55 years;CHD in female first-degree relative 20%)100100130(100129:drug optional)2+Risk factors(10-year risk 20%)13013010-year risk 10%20%:13010-year risk 10%:16001 Risk factor160160190(160189:LDL-Clowering drug optional)Age*(years)Male(%)White(%)Body mass index*(kg/m3)Current smoker(%)Diab
7、etes(%)Hypertension(%)TC*(mg/dLmmol/L)LDL-C*(mg/dLmmol/L)TG*(mg/dLmmol/L)HDL-C*(mg/dLmmol/L)55.89.8719030.56.5262068231.834.2 6.00.9150.227.9 3.90.7197.295.7 2.21.242.39.9 1.10.3 CharacteristicAtorvastatin 80 mg(n=253)REVERSAL:Baseline Characteristics56.69.2738730.55.6271870232.634.1 6.00.9150.225.9
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