神经元和神经胶质细胞-胶质细胞教学文案.ppt
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1、神经元和神经胶质细胞-胶质细胞 Still waters run deep.流静水深流静水深,人静心深人静心深 Where there is life,there is hope。有生命必有希望。有生命必有希望Types and Functions of GliaName of Glial CellFunctionAstrocyte(Astroglia)Star-shaped cells that provide physical and nutritional support for neurons:1)clean up braindebris;2)transport nutrients t
2、o neurons;3)hold neurons in place;4)digest parts of dead neurons;5)regulate content of extracellular space MicrogliaLike astrocytes,microglia digest parts of dead neurons.Oligo-dendrogliaProvide the insulation(myelin)to neurons in the central nervous system.Satellite CellsPhysical support to neurons
3、 in the peripheral nervous system.Schwann CellsProvide the insulation(myelin)to neurons in the peripheral nervous system.Neuroglia Neuroglia in the CNSin the CNSAble to replicate!Importance in nervous system function is VASTLY underestimated!Evidence is mounting:1.Nurturing role2.Signaling role(Memo
4、ry?)3.Inflammation4.Pain5.Many more to come!Neuroglia:Neuroglia:Distinguishing FeaturesDistinguishing Features1.Presence of tight junctions between the endothelial cells2.One of the notable features of endothelial cells in comparison to other cell is the lack of pinocytic vesicles3.Selective permeab
5、ility to molecules based on their molecular weight and lipid solubility4.Presence of specific markersRich in two enzymes:gamma glutamyl transpeptidase(GGTP)(for amino acid transport)and alkaline phosphatase(transport of phsopahte ions)used as marker for BBB.Others:glucose transporter(GLUT-1);endothe
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- 神经元 神经 胶质 细胞 教学 文案
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